Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial...
The use of topical corticosteroids as an adjunctive treatment to antibiotics in the management of bacterial keratitis remains a controversial issue. The results of the...
Conjunctiva is composed of non-squamous epithelial cells interspersed with goblet cells, which is a secretory epithelium. Squamous metaplasia is a transformation to non-secretory epithelium, ‘keratinised’...
This is one of many studies published / to be published on corneal collagen cross-linking that has a treatment time of 10 minutes compared to...
The cornea is an immune privileged site and as such corneal transplants are very successful. However, in situations where this privilege is lost the failure...
Fluoroquinolones, including second generation (ofloxacin and ciprofloxacin), third generation (levofloxacin and tosufloxacin) and fourth generation (gatifloxacin and moxifloxacin), are a group of bactericidal agents used...
The authors present an overview of the aetiology, diagnosis, current and future management options of neurotrophic keratitis. This is a degenerative corneal disease that occurs...
Ocular surface squamous neoplasia (OSSN) comprises a range of dysplasia including corneal-conjunctival intraepithelial neoplasia and invasive squamous cell carcinoma. The traditional treatment for localised non-invasive...
This prospective longitudinal study examined patients 18 years of age or less with progressive keratoconus, who underwent corneal crosslinking and completed 10 years of follow-up....
MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression....
The cornea is exposed to hypoxia under several conditions including sleep, inflammation and wound healing. Being an avascular tissue to maintain transparency, how the cornea...
This was a prospective, interventional case series of 10 eyes from 10 patients who underwent hemi-descemet membrane endothelial keratoplasty (hemi-DMEK) for Fuchs endothelial dystrophy. The...